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Dr Jiangyun LUO, Dennis

 
SCI-indexed publications

  • He L, Chen QH, Wang L, Pu YJ, Huang J, Cheng CK, Luo JY, Kang LJ, Lin X, Xiang L, Fang L, He B, Xia Y, Lui KO, Pan Y, Liu J, Zhang CL, Huang Y (2024) Activation of Nrf2 inhibits atherosclerosis in ApoE-/- mice through suppressing endothelial cell inflammation and lipid peroxidation. Redox Biology 74(2024):103229

  • Cheng CK, Lin X, Pu Y, Tse KYJ, Wang Y, Zhang CL, Cao X, Lau CW, Huang J, He L, Luo JY, Shih YT, Wan S, Ng CF, Wang L, Ma CWR, JJ Chiu, Chan TF, Tian XY & Huang Y (2022) SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis. Journal of Advanced Research (In press)
  • Luo JY, Cheng CK, He L, Pu Y, Zhang Y, Lin X, Xu A, Lau CW, Tian XY, Ma RCW, Jo H & Huang Y (2022) Endothelial UCP2 is a mechanosensitive suppressor of atherosclerosis. Circulation Research 131(5):424-441.
  • Zhang H, Xiang L, Huo M, Wu Y, Yu M, Lau CW, Tian D, Gou L, Huang Y, Luo JY, Wang L, Song W, Huang J, Cai Z, Chen S, Tian XY & Huang Y (2022)  Branched-chain amino acid supplementation Impairs Insulin Sensitivity and Promotes Lipogenesis During Exercise in Diet-Induced Obese Mice. Obesity (Silver Spring). 30(6):1205-1218.
  • Cheng CK, Shang W, Liu J, Cheang WS, Wang Y, Xiang L, Lau CW, Luo JY, Ng CF, Huang Y, Wang L (2022) Activation of AMPK/miR-181b Axis Alleviates Endothelial Dysfunction and Vascular Inflammation in Diabetic Mice. Antioxidants 11(6):1137 (17 pages).
  • Zhao L, Zhang CL, He L, Chen QH, Liu L, Kang L, Liu J, Luo JY, Gou L, Qu D, Song W, Lau CW, Ko H, Mok VCT, Tian XY, Wang L & Huang Y (2022) Restoration of Autophagic Flux Improves Endothelial Function in Diabetes Through Reducing Mitochondrial ROS-mediated eNOS Monomerization. Diabetes 71(5):1099-1114.
  • Cheng CK, Luo JY, Lau CW, Cho WCS, Ng CF, Ma RCW, Tian XY & Huang Y (2021) A GLP-1 analog lowers ER stress and enhances protein folding to ameliorate homocysteine-induced endothelial dysfunction. Acta Pharmacological Sinica 42(10):1598-1609.
  • Huang J, Pu Y, Zhang H, Xie L, He L, Zhang C, Cheng CK, Huo Y, Wan S, Chen S, Huang Y, Lau CW, Wang L, Xia Yin, Huang Y & Luo JY (2021) Endothelial KLF2 mediates the suppressive effect of laminar flow on vascular calcification by inhibiting BMP/SMAD1/5 signaling. Circulation Research 129(4):e87-e100.
  • Cheng CK, Wang C, Shang W, Lau CW, Luo JY, Wang L & Huang Y (2021) A high methionine and low folate diet alters glucose homeostasis and gut microbiome. Biochemistry and Biophysics Reports 24 (March 2021): article 100921
  • Cheng CK, Luo JY, Lau CW, Chen ZY, Tian XY & *Huang Y (2019) Pharmacological Basis and New Insights of Resveratrol Action in the Cardiovascular System. British Journal of Pharmacology 177(6):1258-1277.
  • Song W, Zhang CL, Gou L, He L, Gong YY, Dan Q, Zhao L, Jin N, Chan TF, Wang L, Tian XY, *Luo JY & *Huang Y (2019) Endothelial TFEB (Transcription Factor EB) Restrains IKK (IκB Kinase)-p65 Pathway to Attenuate Vascular Inflammation in Diabetic db/db Mice. Arteriosclerosis, Thrombosis and Vascular Biology 39(4):719-730. (Co-responding author)
  • Gong Y, Luo JY, Wang L & Huang Y (2017) MicroRNAs regulating reactive oxygen species in cardiovascular diseases.Antioxidants & Redox Signaling 29(11):1092-1107

  • Gou L, Zhao L, Song W, Wang L, Liu J, Zhang H, Huang Y, Lau CW, Yao XQ, Tian XY, Wong WT, Luo JY & Huang Y (2017) Inhibition of miR-92a suppresses oxidative stress and improves endothelial function by upregulating heme oxygenase-1 in db/db mice. Antioxidants & Redox Signaling 28(5):358-370 (Co-corresponding author).

  • Wang L, Luo JY, Li B, Tian XY, Chen LJ, Huang Y, Liu J, Deng D, Lau CW, Wan S, Ai D, Mak KL, Tong KK, Kwan KM, Wang N, Chiu JJ, Zhu Y & Huang Y (2016) Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow.Nature 540:579-581. Commented in Nature News and Views, Nature 540:531-532.

  • Zhang H, Liu J, Qu D, Wang L, Luo JY, Lau CW, Liu P, Gao Z, Tipoe, GL, Lee HK, Ng CF, Ma RCW, Yao X & Huang Y (2016) Inhibition of miR-200c restores endothelial function in diabetic mice through suppression of COX-2. Diabetes 65(5):1196-1207 with Commentary Diabetes 65(5):1152-1154.
  • Hu W, Zhang Y, Wang L, Lau CW, Xu J, Luo JY, Gou L, Yao XY, Chen ZY, Ma RCW, Tian XY & Huang Y (2016) Bone morphogenic protein 4-Smad induced upregulation of platelet-derived growth factor AA impairs endothelial function. Arteriosclerosis, Thrombosis and Vascular Biology 36(3):553-560.
  • Zhang Y, Liu J, Luo JY, Tian XY, Cheang WS, Xu J, Lau CW, Wang L, Wong WT, Wong CM, Lan HY, Yao XQ, Raizada MK & Huang Y (2015) Upregulation of angiotensin (1-7)-mediated signaling preserves endothelial function through reducing oxidative stress in diabetes. Antioxidants & Redox Signaling 23(11):880-892 with Cover Image of the Issue.
  • Luo JY, Zhang Y, Wang L & Huang Y (2015) Regulators and effectors of BMP signaling in the cardiovascular system. The Journal of Physiology 593(14):2995-3011
  • Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo JY, Cheang WS, Lau CW, Kwan KM, Wang N, Yao X & Huang Y (2014) Inhibition of bone morphogenic protein-4 restores endothelial function in db/db diabetic mice. Arteriosclerosis, Thrombosis and Vascular Biology 34(1):152-159